I have used Continental Grand Prix 4000 tires on all my bikes since they were first released and I did not think a better road tire could be produced. When I saw that the Grand Prix 5000 was being released, I ordered a pair the same day. The new tire is incredible and has lived up the the claims of faster, more comfortable, and more grip. I am impressed with the improvements.
I have used Conti GP4000s for years and this is the first tire I like better. It has better ride comfort and better grip. The downside is it cuts easily.In addition you must learn some new techniques to get it mounted. The initial bead must be centered in the rim and then you should chase the other bead around the rim until you are able to mount it with your thumbs. A Joe Blow Booster pump (or similar) is required to pop the beads onto the rim - a normal floor pump won't work. A proper amount of sealant is necessary for optimum performance. The increased safety of tubeless technology is worth the hassle.