If the spindle fits.
Use the Chris King #12 Bottom Bracket Conversion Kit with their ThreadFit 24 Bottom Bracket to use 24-22 mm step down road cranksets on 68 mm wide bottom bracket shells. Common road cranks of this type are offered by SRAM, Bontrager, Truvativ, and Zinn.
Comparing bottom bracket types and standards.
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Make your upgrades count. Here's the equipment that will help you ride your bike faster.
Campagnolo vs. Shimano vs. SRAM: demystifying groupsets.
What to consider when selecting a crankset for your road bike.